Francincense - the resin derived from the Bosellia species of trees - has been shown to have multiple healing properties

A gift from the desert: The healing powers of frankincense

27 January, 2014

By Staff Writer
Natural Health News

It was one of the gifts of the Magi – in addition to myrrh and gold they offered frankincense to the newly born baby Jesus.

Frankincense is a resin derived from trees belonging to the Boswellia family, of which there are around 20 different species.

The trees grow naturally in the dry regions spanning from West Africa (where about 75% of all Boswellia trees are found) to Arabia and south to the northeast region of Tanzania. Some can also be found in India and Madagascar.

Boswellia trees have an outer bark that peels away like parchment flakes and a greenish inner bark, which contains the trees’ sap and aromatic resins.

We call these resins frankincense, or olibanum, and the precious resin, sometimes called “pearls of the desert”, is collected either by making an incision in the tree and allowing the resin to flow and harden, or by collecting hardened resin that has flowed naturally from the tree.

The word frankincense is derived from the ancient French name “frankincense,” meaning “pure incense.” Since ancient times the aromatic fragrance of burning Boswellia resin has been part of many religious ceremonies and is still used as a means to indicate special festive atmosphere in the church today.

But frankincense can do much more: “The resin from the trunk of Boswellia trees contains anti-inflammatory substances,” says Professor Dr Oliver Werz of the Friedrich Schiller University Jena, in Germany commenting on his own research in 2011.

A potent anti-inflammatory

Frankincense is a well-known anti-inflammatory. Of the more than 300 known active ingredients in frankincense extract, boswellic acids are the most well-studied.

Examining the curative effect of frankincense, Professor Werz and his colleagues were able to show where exactly how boswellic acids – which are responsible for the impact of the ingredients of the Boswellia resin – interfere in the process of inflammation.

“Boswellic acids interact with several different proteins that are part of inflammatory reactions, but most of all with an enzyme which is responsible for the synthesis of prostaglandin E2, [these] acids block this enzyme efficiently and thereby reduce the inflammatory reaction,” he says.

Prostaglandin E2 is one of the mediators of the immune response and plays a decisive role in the process of inflammation, in the development of fever and of pain.

Werz says he is convinced that the active substances can be very beneficial in therapies against diseases like asthma, rheumatoid arthritis or atopic dermatitis.

Fewer adverse effects

In addition to a new, targeted use in the treatment of inflammatory diseases, boswellic acids also have the advantage of producing fewer adverse effects than today’s prevalent anti-inflammatory treatments like diclofenac or indometacin. The impact of these common drugs is less specific, according to Werz, and unlike boswellic acids, they can increase the risk of stomach ulcers and can harm the kidneys.

Frankincense on the other hand has shown few adverse effects (oral doses can produce some nausea and stomach upset) and no known interactions with conventional drugs.

Different species, different effects

In the Werz’s study, researchers compared the anti-inflammatory effects of the resin of several different kinds of frankincense.

The most well-known and widely-used species of Boswellia is the Boswellia serrata from Northern and central India.

However says Professor Werz of his study, “We were able to show that the resin of the Boswellia papyrifera is ten times more potent”. This species mostly occurs in the Northeast of Africa (Ethiopia, Somalia) and on the Arabian Peninsula (Yemen, Oman).

Clearly we still have much to learn about the therapeutic differences between Boswellia species.

Gathering the evidence

Frankincense is a mainstay of Ayurvedic medicine and a recent raft of studies has shown explored its healing potential.

Taken orally, capsules containing Boswellia frereana have been shown to ease painful arthritis. Boswellia carterii has similarly been shown to be anti-inflammatory.

Animal studies and pilot clinical trials in humans support the potential of Boswellia serrata gum resin extract (BSE) for the treatment of a variety of inflammatory diseases like inflammatory bowel disease, rheumatoid arthritis, osteoarthritis and asthma. It has also been shown to be effective in treating chronic cluster headaches.

Indeed, in 20o8 a well known alternative medicine sceptic, who reviewed the evidence for the medicinal properties of frankincense (in this case B serrata) in the British Medical Journal found that Boswellia extracts showed some promise in treating asthma, rheumatoid arthritis, Crohn’s disease, knee osteoarthritis, where one trial found that the effect lasted longer than when patients took valdecoxib, a selective COX-2 inhibitor and collagenous colitis.

He was moved to conclude that the evidence was “encouraging” for in treating a range of conditions caused or maintained by inflammatory processes, though more evidence is needed.

Boswellia serrata extract also exhibits anti-bacterial and anti-fungal activities. There is also laboratory evidence suggesting that Boswellia carterii possesses anti-cancer properties, though no human studies have shown this yet.

Adding to the interesting findings in cancer studies, in 2013 researchers from the University of Leicester in the UK, released the findings of a study, ahead of publication, which showed that the AKBA (acetyl-11-keto-beta-boswellic) compound found in frankincense and ovarian cancer cells in a lab. Previous studies have linked the AKBA and other active compounds in frankincense as potential treatments for other cancers including colorectal, pancreatic and breast cancer (in these last two studies it was B. sacra essential that was found to be effective).

Protecting an endangered species

The research into the medicinal qualities of frankincense, as well as its widespread use in perfumery and cosmetics, throws up several questions about the sustainable production of the tree, however.

“Boswellic acids exclusively occur in the resin of Boswellia trees and are very difficult to produce synthetically,“ Professor Werz points out. Therefore these trees are the only source of these promising active ingredients.

However several species of Boswellia trees, including Boswellia papyrifera which grows in Northern Ethiopia, are already endangered.

Ethiopia is, in fact, worldwide the main producer of frankincense and myrrh, and exports large quantities of gum arabic.

In a study of frankincense production in 2011 the researchers noted that extraction of the resin does not threaten the survival of the trees in any way.

While sustainable gum/resin production could significantly contribute towards sustainable development of what are often marginal dry lands, it is years of improper land use (overgrazing, over-harvesting of gum/resins and wood) threatens the sustainability of the frankincense tree and as a result of that also the long-term gum/resin production. In addition infestation by the longhorn beetle is threatening the planting of new trees.

In some impoverished countries the trees are simply being used as heating fuel.

“Without sustained protection not only plant species are endangered but at the same time medicine loses promising active ingredients,” Professor Werz warns.